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A message left behind by the Kai Opaka gives Commander Benjamin Sisko a fateful mission: find a young Bajoran girl destined to be a great healer who could bring together the warring factions of Bajor. While Lt. Dax tries to find the healer, Dr. Bashir goes planetside to treat a rare disease that is killing the children in Bajor's resettlement camps. Surrounded by thousands of dying children, Bashir goes A.W.O.L. from Deep Space Nine, vowing not to return until the plague has been stopped. But by the time Dax finds the girl from the Kai's prophecy the child has fallen victim to the plague. Now, with the fate of the entire planet at stake, Commander Sisko must find Dr. Bashir in time to save the child who may be Bajor's last chance for peace.

The Starship Enterprise NX-01 is humanity's flagship – the first starship to begin a systematic exploration of what lies beyond the fringes of known space. Led by Captain Jonathan Archer, eighty of Starfleet's best and brightest set forth to pave humanity's way among the stars. Tempered by a year's worth of exploration, they are a disciplined, cohesive unit. But now one of their number has fallen. Bad enough that Ensign Alana Hart is dead. Worse still that she died while trying to sabotage the Enterprise – and at the hands of Lieutenant Malcolm Reed, the ship's armory officer and her nominal superior. Even as questions swirl around Hart's death, Archer, Reed, and the rest of the Enterprise crew find themselves caught squarely in the middle of another tense situation – a brutal war of terror between two civilizations. But in the Eris Alpha system, nothing – and no one – are what they seem. And before the secret behind Ensign Hart's demise is exposed, Reed will be forced to confront death one more time.

In a desperate attempt to prevent the artificial intelligence known as Control from seizing crucial information that could destroy all sentient life, Commander Michael Burnham donned the 'Red Angel' time-travel suit and guided the USS Discovery into the future and out of harm's way. But something has gone terribly wrong, and Burnham has somehow arrived in a place far different from anything she could have imagined – more than nine hundred years out of her time, with Discovery nowhere to be found, and where the mysterious and cataclysmic event known as 'the Burn' has utterly decimated Starfleet and, with it, the United Federation of Planets. How then can she possibly exist day-to-day in this strange place? What worlds are out there waiting to be discovered? Do any remnants of Starfleet and the Federation possibly endure? With more questions than answers, Burnham must nevertheless forge new friendships and new alliances if she hopes to survive this future long enough for the Discovery crew to find her...